Addressing the treatment of macrophage activation syndrome: A challenging balance between immune suppression and infectious risk

Vassia V, Iannaccone A, Marengo S, Briozzo A, Brussino A, Alessi L, Brussino L and Norbiato C*

Hemophagocytic Lymphohistiocytosis (HLH) is a rare and potentially life-threatening syndrome related to a dysregulation of cytolytic function of Natural Killer (NK) cells and cytotoxic T cells (CTLs), which in turns leads to an inappropriate immune stimulation and hyperinflammatory state, resulting in hypercytokinemia, accumulation of activated lymphocytes and macrophages [1,2].

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Published on: Aug 13, 2022 Pages: 11-14

Full Text PDF Full Text HTML DOI: 10.17352/2455-5363.000052
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