A Short Review on Advances in Nanosystems Emerging as an Effective Approaches to Control Pathogenesis of Staphylococcus spp

Ved Prakash Giri, Pallavi Shukla, Ashutosh Tripathi, Navinit Kumar, Priya Verma, Shipra Pandey and Aradhana Mishra*

Nanomaterials in drug delivery systems are emerging as a potential source of treatments. The bioavailability of nano-carriers depends upon various factors including their mode of administration, target specificity, availability of active compound and compatibility with biological system. Due to ingenious survival strategies many antibiotics become ineffective in the treatment of Staphylococcus spp. causing diseases. Though, nanosystems have been developed as an emerging approach to vanquish the obstacles for the treatment of Staphylococcus spp infections. Due to their encouraging and substantial outcomes, this review focused on the exploration of advances in nanosystems and their curing mechanism to control the infection of Staphylococcus spp. Several nanosystems are previously reported and compiled herein, which may use as a treatment of Staphylococcus causing diseases as well as inhibition of biofilm formation. Pathogenesis mechanisms such as immune clearance, membrane permeability and production of β-lactamase also described briefly in this review. 

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Published on: Aug 19, 2021 Pages: 49-55

Full Text PDF Full Text HTML DOI: 10.17352/2455-5363.000046
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