A strategy for finding new medicines against the novel coronavirus disease (COVID-19) derived from base pairing with DNA damages

Katsuhito Kino*, Takayuki Ohshima, Taishu Kawada, Takanobu Kobayashi and Hiroshi Miyazawa

The spread of the novel coronavirus disease (COVID-19) has caused a global pandemic. Exiting agents that act on proteins including 3-chymotrypsin-like protease (3CLpro), papain-like protease (PLpro), helicase, RNA-dependent RNA polymerase (RdRp), spike glycoprotein (S protein), and others in similar viruses [1,2] are likely used as antiviral drugs against the novel coronavirus (SARS-CoV-2). Data on Chemical Abstract Service show that the potential drug candidates against 3CLpro and RdRp are more than those against other targets [2].

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Published on: Dec 22, 2020 Pages: 60-61

Full Text PDF Full Text HTML DOI: 10.17352/2455-5363.000038
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